Pre-exposure vaccination for the rabies virus is necessary for anyone who, because of occupation or travel destinations, is at risk for rabies exposure. Those professionals at risk include, but are not limited to, veterinarians and staff, animal handlers, wildlife officers, and certain laboratory workers who work with the rabies virus.1

Globally, dogs are the main carriers of the rabies virus, and rabies is found in all continents except Antarctica.2 International travelers should consider pre-exposure vaccination if they are likely to come in contact with animals in areas where rabies in dogs is common and immediate access to appropriate medical care might be limited.1 Canine rabies is found in most countries within Africa, Asia, and Central and South America.2

Pre-exposure vaccination does not eliminate the need for postexposure treatment; pre- exposure vaccination merely simplifies the therapy by eliminating the need for immune globulin and decreasing the number of vaccine doses.1 Whether a patient has received pre-exposure vaccination or not, anyone exposed to the rabies virus must be given postexposure treatment.
References: 1. Centers for Disease Control and Prevention (CDC). Human rabies prevention—United States, 1999: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Morb Mortal Wkly Rep. 1999;48(RR-1):1-21. 2. CDC. Health Information for International Travel 2001-2002. Atlanta, Ga: US Dept of Health and Human Services; 2001:133-138.